Age-related changes in core body temperature and activity in triple-transgenic Alzheimer's disease (3xTgAD) mice

EM Knight, TM Brown, S Gümüsgöz… - Disease models & …, 2013 - journals.biologists.com
… that there are age-related changes in core body temperature and activity rhythms in 3xTgAD
mice that precede significant AD pathology. Alterations in temperature and activity might …

[HTML][HTML] Age Related Changes in Muscle Mass and Force Generation in the Triple Transgenic (3xTgAD) Mouse Model of Alzheimer's Disease

H Xu, S Bhaskaran, KM Piekarz, R Ranjit… - Frontiers in Aging …, 2022 - frontiersin.org
… To investigate whether pathological changes associated with … used the triple transgenic
mouse model of AD (3xTgAD mice) that … We measured changes in motor neurons and skeletal …

Hypermetabolism in a triple-transgenic mouse model of Alzheimer's disease

EM Knight, A Verkhratsky, SM Luckman, SM Allan… - Neurobiology of …, 2012 - Elsevier
… study, using a triple-transgenic (3xTgAD) mouse model of AD… Alzheimer's disease (AD) is
an age-related … expended (eg, an increase in metabolic rate and/or activity). Food intake in …

Impaired thermoregulation and beneficial effects of thermoneutrality in the 3× Tg-AD model of Alzheimer's disease

M Vandal, PJ White, M Tournissac, C Tremblay… - Neurobiology of …, 2016 - Elsevier
… measured the body temperature of triple-transgenic mouse model … The 3×Tg-AD mouse
model of AD displays an age-related … dysfunction of entorhinal cortex neurons in 3xTg-AD mice

[引用][C] P1‐141: Altered core body temperature in triple transgenic (3xTgAD) Alzheimer's disease mice

SM Allan, J Smith, E Waters, E Knight… - Alzheimer's & …, 2010 - Wiley Online Library
activity. … age-related multiple cognitive dysfunctions (contextual, working, episodic-like and
spatial memory) were observed until 6 month of age in Tg2576 mice, indicating that the mice

Age and gender differences for the behavioral phenotypes of 3xTg Alzheimer's disease mice

T Pairojana, S Phasuk, P Suresh, SP Huang… - Brain Research, 2021 - Elsevier
… of the triple transgenic Alzheimer’s disease (3xTg-AD) mice in … The difference between naïve
and trained activities of the 3xTg and … Age-related changes in neuroactive steroid levels in …

Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease

VKM Halagappa, Z Guo, M Pearson, Y Matsuoka… - … of disease, 2007 - Elsevier
… CR and/or IF could ameliorate age-related behavioral impairments in 3xTgAD mice. …
age-related decrease in open-field activity in 3xTgAD mice is attenuated by CR and IF 3xTgAD mice

Abnormal circadian locomotor rhythms and Per gene expression in six-month-old triple transgenic mice model of Alzheimer's disease

M Wu, F Zhou, X Cao, J Yang, Y Bai, X Yan, J Cao… - Neuroscience …, 2018 - Elsevier
… -old triple transgenic AD mouse model (3xTg-AD) without … are more susceptible to age-related
circadian dysfunction than … Age-related changes in core body temperature and activity in …

[HTML][HTML] Changes in 24 h rhythmicity of spontaneous locomotor activity in the triple transgenic mouse for Alzheimer's disease (3xTg-AD) in a jet lag protocol …

IA González-Luna, C Juárez-Tapia… - Journal of Circadian …, 2021 - ncbi.nlm.nih.gov
… the nocturnal locomotor activity, increased body temperature, … ) and triple transgenic mice
for Alzheimer disease (3xTg-AD). … age-related changes in the circadian system like changes in …

[HTML][HTML] Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model

X Lin, L Chen, D Baglietto-Vargas, P Kamalipour… - … of disease, 2022 - Elsevier
activities imaged at single cell resolution in a triple-transgenic Alzheimer's disease mouse
model (3xTg-AD) … pathological features along with age-related behavioral defects. To measure …